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1

Rheumatoid arthritis

Smolen, Josef S., Aletaha, Daniel, Barton, Anne, Burmester, Gerd R., Emery, Paul, Firestein, Gary S., Kavanaugh, Arthur, McInnes, Iain B., Solomon, Daniel H., Strand, Vibeke, Yamamoto, Kazuhiko

Journal:

Nature Reviews Disease Primers

Year:

2018

Language:

english

File:

PDF, 8.90 MB

english, 2018

2

The right time to learn: mechanisms and optimization of spaced learning

Smolen, Paul, Zhang, Yili, Byrne, John H.

Journal:

Nature Reviews Neuroscience

Year:

2016

Language:

english

File:

PDF, 614 KB

english, 2016

3

Computational Analyses of Synergism in Small Molecular Network Motifs

Zhang, Yili, Smolen, Paul, Baxter, Douglas A., Byrne, John H., Iakoucheva, Lilia M.

Journal:

PLoS Computational Biology

Year:

2014

Language:

english

File:

PDF, 1.22 MB

english, 2014

4

Pharmacological treatment of psoriatic arthritis: a systematic literature review for the 2015 update of the EULAR recommendations for the management of psoriatic arthritis

Ramiro, Sofia, Smolen, Josef S, Landewé, Robert, van der Heijde, Désirée, Dougados, Maxime, Emery, Paul, de Wit, Maarten, Cutolo, Maurizio, Oliver, Susan, Gossec, Laure

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 2.38 MB

english, 2015

5

Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: A randomized, controlled trial

E. William St. Clair, Désirée M. F. M. van der Heijde, Josef S. Smolen, Ravinder N. Maini, Joan M. Bathon, Paul Emery, Edward Keystone, Michael Schiff, Joachim R. Kalden, Ben Wang, Kimberly DeWoody, R

Journal:

Arthritis & Rheumatism

Year:

2004

Language:

english

File:

PDF, 139 KB

english, 2004

6

Dynamic Properties of Regulatory Motifs Associated with Induction of Three Temporal Domains of Memory inAplysia

David B. Pettigrew, Paul Smolen, Douglas A. Baxter, John H. Byrne

Journal:

Journal of Computational Neuroscience

Year:

2005

Language:

english

File:

PDF, 610 KB

english, 2005

7

Infliximab (chimeric anti-tumour necrosis factor α monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial

Ravinder Maini, E William St Clair, Ferdinand Breedveld, Daniel Furst, Joachim Kalden, Michael Weisman, Josef Smolen, Paul Emery, Gregory Harriman, Marc Feldmann, Peter Lipsky

Journal:

Year:

1999

Language:

english

File:

PDF, 133 KB

english, 1999

8

Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis

Lipsky, Peter E., van der Heijde, Desiree M.F.M., St. Clair, E. William, Furst, Daniel E., Breedveld, Ferdinand C., Kalden, Joachim R., Smolen, Josef S., Weisman, Michael, Emery, Paul, Feldmann, Marc,

Journal:

Boston Medical and Surgical Journal

Year:

2000

Language:

english

File:

PDF, 131 KB

english, 2000

9

Properties of a Bursting Model with Two Slow Inhibitory Variables

Smolen, Paul, Terman, David, Rinzel, John

Journal:

SIAM Journal on Applied Mathematics

Year:

1993

Language:

english

File:

PDF, 4.01 MB

english, 1993

10

Properties of a Bursting Model with Two Slow Inhibitory Variables

Paul Smolen, David Terman and John Rinzel

Journal:

SIAM Journal on Applied Mathematics

Year:

1993

Language:

english

File:

PDF, 3.86 MB

english, 1993

11

Consensus-based recommendations for the use of biosimilars to treat rheumatological diseases

Kay, Jonathan, Schoels, Monika M, Dörner, Thomas, Emery, Paul, Kvien, Tore K, Smolen, Josef S, Breedveld, Ferdinand C

Journal:

Annals of the Rheumatic Diseases

Year:

2017

Language:

english

File:

PDF, 376 KB

english, 2017

12

Conversion to seronegative status after abatacept treatment in patients with early and poor prognostic rheumatoid arthritis is associated with better radiographic outcomes and sustained remission: post hoc analysis of the AGREE study

Jansen, Diahann T S L, Emery, Paul, Smolen, Josef S, Westhovens, Rene, Le Bars, Manuela, Connolly, Sean E, Ye, June, Toes, René E M, Huizinga, Tom W J

Journal:

Year:

2018

Language:

english

File:

PDF, 1.63 MB

english, 2018

13

How can memories last for days, years, or a lifetime? Proposed mechanisms for maintaining synaptic potentiation and memory

Smolen, Paul, Baxter, Douglas A., Byrne, John H.

Journal:

Learning & Memory

Year:

2019

Language:

english

File:

PDF, 2.52 MB

english, 2019

14

Doubtful swelling on clinical examination reflects synovitis in rheumatoid arthritis

Mandl, Peter, Studenic, Paul, Supp, Gabriela, Durechova, Martina, Haider, Stefanie, Lehner, Michaela, Stamm, Tanja, Smolen, Josef S., Aletaha, Daniel

Journal:

Therapeutic Advances in Musculoskeletal Diseases

Year:

2020

File:

PDF, 978 KB

2020

15

Endothelial precursor cells in the synovial tissue of patients with rheumatoid arthritis and osteoarthritis

Beate Rüger, Alexander Giurea, Axel H. Wanivenhaus, Harald Zehetgruber, David Hollemann, Genya Yanagida, Marion Groger, Peter Petzelbauer, Josef S. Smolen, Paul Hoecker, Michael B. Fischer

Journal:

Arthritis & Rheumatism

Year:

2004

Language:

english

File:

PDF, 511 KB

english, 2004

16

Infliximab treatment maintains employability in patients with early rheumatoid arthritis

Josef S. Smolen, Chenglong Han, Désirée Van Der Heijde, Paul Emery, Joan M. Bathon, Edward Keystone, Joachim R. Kalden, Michael Schiff, Mohan Bala, Daniel Baker, John Han, Ravinder N. Maini, E. Willia

Journal:

Arthritis & Rheumatism

Year:

2006

Language:

english

File:

PDF, 92 KB

english, 2006

17

Effect of certolizumab pegol with methotrexate on home and work place productivity and social activities in patients with active rheumatoid arthritis

Arthur Kavanaugh, Josef S. Smolen, Paul Emery, Oana Purcaru, Edward Keystone, Lance Richard, Vibeke Strand, Ronald F. van Vollenhoven

Journal:

Arthritis Care & Research

Year:

2009

Language:

english

File:

PDF, 418 KB

english, 2009

18

Metabolic requirements for maintenance of the chlortetracycline-labeled pool of membrane-bound calcium in human neutrophils

James E. Smolen, Paul Noble, Richard Freed, Gerald Weissmann

Journal:

Journal of Cellular Physiology

Year:

1983

Language:

english

File:

PDF, 808 KB

english, 1983

19

Bioavailability and pharmacokinetic analysis of chlorpromazine-induced rectal temperature depression in rabbits

Victor F. Smolen, Ashok K. Jhawar, William A. Weigand, Ronald M. Paolino, Paul B. Kuehn

Journal:

Journal of Pharmaceutical Sciences

Year:

1976

Language:

english

File:

PDF, 621 KB

english, 1976

20

Pharmacokinetics of chlorpromazine-induced miotic response in rabbits

Paul B. Kuehn, Ashok K. Jhawar, William A. Weigand, Victor F. Smolen

Journal:

Journal of Pharmaceutical Sciences

Year:

1976

Language:

english

File:

PDF, 772 KB

english, 1976

21

Modeling Transcriptional Control in Gene Networks—Methods, Recent Results, and Future Directions

Paul Smolen, Douglas A. Baxter, John H. Byrne

Journal:

Bulletin of Mathematical Biology

Year:

2000

Language:

english

File:

PDF, 516 KB

english, 2000

22

Phase Independent Resetting in Relaxation and Bursting Oscillators

Paul Smolen, Arthur Sherman

Journal:

Journal of Theoretical Biology

Year:

1994

File:

PDF, 536 KB

1994

23

A model for glycolytic oscillations based on skeletal muscle phosphofructokinase kinetics

Journal:

Journal of Theoretical Biology

Year:

1995

Language:

english

File:

PDF, 631 KB

english, 1995

24

Kinetics and thermodynamics of metabolite transfer between enzymes

Paul Smolen, Joel Keizer

Journal:

Biophysical Chemistry

Year:

1990

Language:

english

File:

PDF, 2.19 MB

english, 1990

25

Slow voltage inactivation of Ca2+currents and bursting mechanisms for the mouse pancreatic beta-cell

Paul Smolen, Joel Keizer

Journal:

Journal of Membrane Biology

Year:

1992

Language:

english

File:

PDF, 970 KB

english, 1992

26

Trends in prices to commercial energy consumers in the competitive Texas electricity market

Jay Zarnikau, Marilyn Fox, Paul Smolen

Journal:

Year:

2007

Language:

english

File:

PDF, 207 KB

english, 2007

27

Predictors of joint damage in patients with early rheumatoid arthritis treated with high-dose methotrexate with or without concomitant infliximab: Results from the ASPIRE trial

Josef S. Smolen, Désirée M. F. M. Van Der Heijde, E. William St.Clair, Paul Emery, Joan M. Bathon, Edward Keystone, Ravinder N. Maini, Joachim R. Kalden, Michael Schiff, Daniel Baker, Chenglong Han, J

Journal:

Arthritis & Rheumatism

Year:

2006

Language:

english

File:

PDF, 118 KB

english, 2006

28

Sex differences in the recovery of brain acetylcholinesterase activity following a single exposure to DFP

Andrew Smolen, Toni N. Smolen, Paul C. Han, Allan C. Collins

Journal:

Pharmacology Biochemistry and Behavior

Year:

1987

Language:

english

File:

PDF, 733 KB

english, 1987

29

Alterations in regional brain GABA concentration and turnover during pregnancy

Andrew Smolen, Toni Ness Smolen, Paul C. Han

Journal:

Pharmacology Biochemistry and Behavior

Year:

1993

Language:

english

File:

PDF, 775 KB

english, 1993

30

Adolescent pregnancy: Involvement of the male partner

Rosalind Vaz, Paul Smolen, Charlene Miller

Journal:

Journal of Adolescent Health Care

Year:

1983

Language:

english

File:

PDF, 446 KB

english, 1983

31

Discrepancies between patients and physicians in their perceptions of rheumatoid arthritis disease activity

Paul Studenic, Helga Radner, Josef S. Smolen, Daniel Aletaha

Journal:

Arthritis & Rheumatism

Year:

2012

Language:

english

File:

PDF, 170 KB

english, 2012

32

The 5-HT- and FMRFa-activated signaling pathways interact at the level of the Erk MAPK cascade: Potential inhibitory constraints on memory formation

Diasinou Fioravante, Paul D. Smolen, John H. Byrne

Journal:

Neuroscience Letters

Year:

2006

Language:

english

File:

PDF, 283 KB

english, 2006

33

Repair of Local Bone Erosions and Reversal of Systemic Bone Loss Upon Therapy with Anti-Tumor Necrosis Factor in Combination with Osteoprotegerin or Parathyroid Hormone in Tumor Necrosis Factor-Mediated Arthritis

Kurt Redlich, Birgit Görtz, Silvia Hayer, Jochen Zwerina, Nicholas Doerr, Paul Kostenuik, Helga Bergmeister, George Kollias, Günter Steiner, Josef S. Smolen, Georg Schett

Journal:

The American Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 3.06 MB

english, 2004

34

Mathematical Modeling of Gene Networks

Paul Smolen, Douglas A Baxter, John H Byrne

Journal:

Year:

2000

Language:

english

File:

PDF, 371 KB

english, 2000

35

Computational design of enhanced learning protocols

Zhang, Yili, Liu, Rong-Yu, Heberton, George A, Smolen, Paul, Baxter, Douglas A, Cleary, Leonard J, Byrne, John H

Journal:

Nature Neuroscience

Year:

2011

Language:

english

File:

PDF, 700 KB

english, 2011

36

From Molecules to Networks || Mathematical Modeling and Analysis of Intracellular Signaling Pathways

Smolen, Paul D.

Year:

2004

Language:

english

File:

PDF, 788 KB

english, 2004

37

A Reduced Model Clarifies the Role of Feedback Loops and Time Delays in the Drosophila Circadian Oscillator

Smolen, Paul, Baxter, Douglas A., Byrne, John H.

Journal:

Biophysical Journal

Year:

2002

Language:

english

File:

PDF, 378 KB

english, 2002

38

Simulation of Drosophila Circadian Oscillations, Mutations, and Light Responses by a Model with VRI, PDP-1, and CLK

Smolen, Paul, Hardin, Paul E., Lo, Brian S., Baxter, Douglas A., Byrne, John H.

Journal:

Biophysical Journal

Year:

2004

Language:

english

File:

PDF, 468 KB

english, 2004

39

New therapies for treatment of rheumatoid arthritis

Josef S Smolen, Daniel Aletaha, Marcus Koeller, Michael H Weisman, Paul Emery

Journal:

Year:

2007

Language:

english

File:

PDF, 367 KB

english, 2007

40

Segmental analysis of spinal cord monoamines after thoracic transection in the dog

Edward S. Stanton, Paul M. Smolen, Blaine S. Nashold Jr., Duane A. Dreyer, James N. Davis

Journal:

Year:

1975

Language:

english

File:

PDF, 696 KB

english, 1975

41

Antibody response to oral polio vaccine in premature infants

Paul Smolen, Regina Bland, Eric Heiligenstein, Michael R. Lawless, Robert Dillard, Jon Abramson

Journal:

The Journal of Pediatrics

Year:

1983

Language:

english

File:

PDF, 256 KB

english, 1983

42

Calcium and Glycolysis Mediate Multiple Bursting Modes in Pancreatic Islets

Bertram, Richard, Satin, Leslie, Zhang, Min, Smolen, Paul, Sherman, Arthur

Journal:

Biophysical Journal

Year:

2004

Language:

english

File:

PDF, 244 KB

english, 2004

43

Bifurcation and Singularity Analysis of a Molecular Network for the Induction of Long-Term Memory

Song, Hao, Smolen, Paul, Av-Ron, Evyatar, Baxter, Douglas A., Byrne, John H.

Journal:

Biophysical Journal

Year:

2006

Language:

english

File:

PDF, 368 KB

english, 2006

44

A Model of the Roles of Essential Kinases in the Induction and Expression of Late Long-Term Potentiation

Smolen, Paul, Baxter, Douglas A., Byrne, John H.

Journal:

Biophysical Journal

Year:

2006

Language:

english

File:

PDF, 358 KB

english, 2006

45

Dynamics of a Minimal Model of Interlocked Positive and Negative Feedback Loops of Transcriptional Regulation by cAMP-Response Element Binding Proteins

Song, Hao, Smolen, Paul, Av-Ron, Evyatar, Baxter, Douglas A., Byrne, John H.

Journal:

Biophysical Journal

Year:

2007

Language:

english

File:

PDF, 299 KB

english, 2007

46

Development and Validation of Modified Disease Activity Scores in Rheumatoid Arthritis: Superior Correlation With Magnetic Resonance Imaging-Detected Synovitis and Radiographic Progression

Baker, Joshua F., Conaghan, Philip G., Smolen, Josef S., Aletaha, Daniel, Shults, Justine, Emery, Paul, Baker, Daniel G., Østergaard, Mikkel

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 142 KB

english, 2014

47

Adjustment of therapy in rheumatoid arthritis on the basis of achievement of stable low disease activity with adalimumab plus methotrexate or methotrexate alone: the randomised controlled OPTIMA trial

Smolen, Josef S, Emery, Paul, Fleischmann, Roy, van Vollenhoven, Ronald F, Pavelka, Karel, Durez, Patrick, Guérette, Benoît, Kupper, Hartmut, Redden, Laura, Arora, Vipin, Kavanaugh, Arthur

Journal:

Year:

2014

Language:

english

File:

PDF, 378 KB

english, 2014

48

Molecular Probe Techniques for the Identification of Reductants in Sediments: Evidence for Reduction of 2-Chloroacetophenone by Hydride Transfer

Smolen, Jean M., Weber, Eric J., Tratnyek, Paul G.

Journal:

Environmental Science & Technology

Year:

1999

Language:

english

File:

PDF, 132 KB

english, 1999

49

Reply

Baker, Joshua F., Smolen, Josef S., Aletaha, Daniel, Shults, Justine, Conaghan, Philip G., Emery, Paul, Baker, Daniel G., Østergaard, Mikkel

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 310 KB

english, 2014

50

Infliximab: 12 years of experience

Josef S Smolen,Paul Emery

Journal:

Arthritis Research & Therapy

Year:

2011

Language:

english

File:

PDF, 1.47 MB

english, 2011